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Force Sensing by Extension of the Src Family Kinase Substrate, p130Cas

Physical force is implicated in many cell functions. However, the molecular mechanisms of force sensing are poorly understood. Here, we show that mechanical extension of p130Cas (Cas) in vitro and in vivo causes phosphorylation by Src family kinases with no apparent change in Src kinase activity and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sawada, Yasuhiro, Tamada, Masako, Dubin-Thaler, Benjamin J., Cherniavskaya, Oksana, Sakai, Ryuichi, Tanaka, Sakae, Sheetz, Michael P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746973/
https://ncbi.nlm.nih.gov/pubmed/17129785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.09.044
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