Force Sensing by Extension of the Src Family Kinase Substrate, p130Cas

Physical force is implicated in many cell functions. However, the molecular mechanisms of force sensing are poorly understood. Here, we show that mechanical extension of p130Cas (Cas) in vitro and in vivo causes phosphorylation by Src family kinases with no apparent change in Src kinase activity and...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Sawada, Yasuhiro, Tamada, Masako, Dubin-Thaler, Benjamin J., Cherniavskaya, Oksana, Sakai, Ryuichi, Tanaka, Sakae, Sheetz, Michael P.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746973/
https://ncbi.nlm.nih.gov/pubmed/17129785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.09.044
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki