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Selective Tumor Cell Targeting by the Disaccharide Moiety of Bleomycin

In a recent study, the well documented tumor targeting properties of the antitumor agent bleomycin (BLM) were studied in cell culture using microbubbles that had been derivatized with multiple copies of BLM. It was shown that BLM selectively targeted MCF-7 human breast carcinoma cells, but not the “...

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Bibliographic Details
Main Authors: Yu, Zhiqiang, Schmaltz, Ryan M., Bozeman, Trevor C., Paul, Rakesh, Rishel, Michael J., Tsosie, Krystal S., Hecht, Sidney M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605894/
https://ncbi.nlm.nih.gov/pubmed/23379863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311090e
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