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Hypoglycemia Reduces Vascular Endothelial Growth Factor A Production by Pancreatic Beta Cells as a Regulator of Beta Cell Mass

VEGF-A expression in beta cells is critical for pancreatic development, formation of islet-specific vasculature, and Insulin secretion. However, two key questions remain. First, is VEGF-A release from beta cells coupled to VEGF-A production in beta cells? Second, how is the VEGF-A response by beta c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiao, Xiangwei, Guo, Ping, Chen, Zean, El-Gohary, Yousef, Wiersch, John, Gaffar, Iljana, Prasadan, Krishna, Shiota, Chiyo, Gittes, George K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605682/
https://ncbi.nlm.nih.gov/pubmed/23378532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422949
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