A synopsis of factors regulating beta cell development and beta cell mass

The insulin-secreting beta cells in the endocrine pancreas regulate blood glucose levels, and loss of functional beta cells leads to insulin deficiency, hyperglycemia (high blood glucose) and diabetes mellitus. Current treatment strategies for type-1 (autoimmune) diabetes are islet transplantation,...

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Bibliografiske detaljer
Udgivet i:Cell Mol Life Sci
Main Authors: Prasadan, Krishna, Shiota, Chiyo, Xiangwei, Xiao, Ricks, David, Fusco, Joseph, Gittes, George
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002366/
https://ncbi.nlm.nih.gov/pubmed/27105622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2231-0
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