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Autophagy protects pancreatic beta cell mass and function in the setting of a high-fat and high-glucose diet
Autophagy is a major regulator of pancreatic beta cell homeostasis. Altered autophagic activity has been implicated in the beta cells of patients with type 2 diabetes, and in the beta cells of obese diabetic rodents. Here, we show that autophagy was induced in beta cells by either a high-fat diet or...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703965/ https://ncbi.nlm.nih.gov/pubmed/29180700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16485-0 |
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