Autophagy protects pancreatic beta cell mass and function in the setting of a high-fat and high-glucose diet

Autophagy is a major regulator of pancreatic beta cell homeostasis. Altered autophagic activity has been implicated in the beta cells of patients with type 2 diabetes, and in the beta cells of obese diabetic rodents. Here, we show that autophagy was induced in beta cells by either a high-fat diet or...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Sheng, Qingfeng, Xiao, Xiangwei, Prasadan, Krishna, Chen, Congde, Ming, Yungching, Fusco, Joseph, Gangopadhyay, Nupur N., Ricks, David, Gittes, George K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703965/
https://ncbi.nlm.nih.gov/pubmed/29180700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16485-0
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items