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M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7
Determination of signaling pathways that regulate beta-cell replication is critical for beta-cell therapy. Here, we show that blocking pancreatic macrophage infiltration after pancreatic duct ligation (PDL) completely inhibits beta-cell proliferation. The TGFβ superfamily signaling inhibitor SMAD7 w...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977272/ https://ncbi.nlm.nih.gov/pubmed/24639504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321347111 |
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