Structure of the Human Angiotensin II Type 1 (AT(1)) Receptor Bound to Angiotensin II from Multiple Chemoselective Photoprobe Contacts Reveals a Unique Peptide Binding Mode

Breakthroughs in G protein-coupled receptor structure determination based on crystallography have been mainly obtained from receptors occupied in their transmembrane domain core by low molecular weight ligands, and we have only recently begun to elucidate how the extracellular surface of G protein-c...

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Bibliographische Detailangaben
Hauptverfasser: Fillion, Dany, Cabana, Jérôme, Guillemette, Gaétan, Leduc, Richard, Lavigne, Pierre, Escher, Emanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605637/
https://ncbi.nlm.nih.gov/pubmed/23386604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.442053
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