Structure of the Human Angiotensin II Type 1 (AT(1)) Receptor Bound to Angiotensin II from Multiple Chemoselective Photoprobe Contacts Reveals a Unique Peptide Binding Mode

Breakthroughs in G protein-coupled receptor structure determination based on crystallography have been mainly obtained from receptors occupied in their transmembrane domain core by low molecular weight ligands, and we have only recently begun to elucidate how the extracellular surface of G protein-c...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Fillion, Dany, Cabana, Jérôme, Guillemette, Gaétan, Leduc, Richard, Lavigne, Pierre, Escher, Emanuel
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2013
الموضوعات:
Protein Structure and Folding
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605637/
https://ncbi.nlm.nih.gov/pubmed/23386604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.442053
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