Structural basis for dual roles of Aar2p in U5 snRNP assembly

Yeast U5 small nuclear ribonucleoprotein particle (snRNP) is assembled via a cytoplasmic precursor that contains the U5-specific Prp8 protein but lacks the U5-specific Brr2 helicase. Instead, pre-U5 snRNP includes the Aar2 protein not found in mature U5 snRNP or spliceosomes. Aar2p and Brr2p bind co...

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Bibliografiska uppgifter
Huvudupphovsmän: Weber, Gert, Cristão, Vanessa F., Santos, Karine F., Jovin, Sina Mozaffari, Heroven, Anna C., Holton, Nicole, Lührmann, Reinhard, Beggs, Jean D., Wahl, Markus C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2013
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605466/
https://ncbi.nlm.nih.gov/pubmed/23442228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.213207.113
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