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Mechanism for Aar2p function as a U5 snRNP assembly factor

Little is known about how particle-specific proteins are assembled on spliceosomal small nuclear ribonucleoproteins (snRNPs). Brr2p is a U5 snRNP-specific RNA helicase required for spliceosome catalytic activation and disassembly. In yeast, the Aar2 protein is part of a cytoplasmic precursor U5 snRN...

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Detalhes bibliográficos
Main Authors: Weber, Gert, Cristão, Vanessa F., de L. Alves, Flavia, Santos, Karine F., Holton, Nicole, Rappsilber, Juri, Beggs, Jean D., Wahl, Markus C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182018/
https://ncbi.nlm.nih.gov/pubmed/21764848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.635911
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