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Inhibition of U snRNP assembly by a virus-encoded proteinase

It has been proposed that defects in the assembly of spliceosomal uridine-rich small nuclear ribonucleoprotein (U snRNP) complexes could account for the death of motor neurons in spinal muscular atrophy (SMA). We discovered that infection of cultured cells with poliovirus results in the specific cle...

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Détails bibliographiques
Auteurs principaux: Almstead, Laura L., Sarnow, Peter
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855234/
https://ncbi.nlm.nih.gov/pubmed/17473171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1535607
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