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Assembly of the U1 snRNP involves interactions with the backbone of the terminal stem of U1 snRNA

Nucleotide analog interference mapping (NAIM) is a powerful method for identifying RNA functional groups involved in protein–RNA interactions. We examined particles assembled on modified U1 small nuclear RNAs (snRNAs) in vitro and detected two categories of interferences. The first class affects the...

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Detalhes bibliográficos
Main Authors: McCONNELL, TIMOTHY S., LOKKEN, R. PETER, STEITZ, JOAN A.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by RNA Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370385/
https://ncbi.nlm.nih.gov/pubmed/12554862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2136103
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