Functional organization of the Sm core in the crystal structure of human U1 snRNP

U1 small nuclear ribonucleoprotein (snRNP) recognizes the 5′-splice site early during spliceosome assembly. It represents a prototype spliceosomal subunit containing a paradigmatic Sm core RNP. The crystal structure of human U1 snRNP obtained from natively purified material by in situ limited proteo...

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Hauptverfasser: Weber, Gert, Trowitzsch, Simon, Kastner, Berthold, Lührmann, Reinhard, Wahl, Markus C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018796/
https://ncbi.nlm.nih.gov/pubmed/21113136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.295
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