טוען...

Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated through distinct biochemical mechanisms

The transcription factor Bcl-6 orchestrates the germinal center reaction through its actions in B and T cells, and regulates inflammatory signaling in macrophages. We report that genetic replacement by mutant Bcl-6, which cannot bind corepressors to its BTB domain, disrupted germinal center formatio...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Huang, Chuanxin, Hatzi, Katerina, Melnick, Ari
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604075/
https://ncbi.nlm.nih.gov/pubmed/23455674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2543
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