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BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

Follicular helper T cells (Tfh cells) are required for T cell help to B cells, and BCL6 is the defining transcription factor of Tfh cells. However, the functions of BCL6 in Tfh cells have largely remained unclear. Here we defined the BCL6 cistrome in primary human germinal center Tfh cells to assess...

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Publicado en:J Exp Med
Autores principales: Hatzi, Katerina, Nance, J. Philip, Kroenke, Mark A., Bothwell, Marcella, Haddad, Elias K., Melnick, Ari, Crotty, Shane
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387288/
https://ncbi.nlm.nih.gov/pubmed/25824819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141380
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