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BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

Follicular helper T cells (Tfh cells) are required for T cell help to B cells, and BCL6 is the defining transcription factor of Tfh cells. However, the functions of BCL6 in Tfh cells have largely remained unclear. Here we defined the BCL6 cistrome in primary human germinal center Tfh cells to assess...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Hatzi, Katerina, Nance, J. Philip, Kroenke, Mark A., Bothwell, Marcella, Haddad, Elias K., Melnick, Ari, Crotty, Shane
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387288/
https://ncbi.nlm.nih.gov/pubmed/25824819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141380
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