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BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

Follicular helper T cells (Tfh cells) are required for T cell help to B cells, and BCL6 is the defining transcription factor of Tfh cells. However, the functions of BCL6 in Tfh cells have largely remained unclear. Here we defined the BCL6 cistrome in primary human germinal center Tfh cells to assess...

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Bibliografiska uppgifter
I publikationen:J Exp Med
Huvudupphovsmän: Hatzi, Katerina, Nance, J. Philip, Kroenke, Mark A., Bothwell, Marcella, Haddad, Elias K., Melnick, Ari, Crotty, Shane
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387288/
https://ncbi.nlm.nih.gov/pubmed/25824819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141380
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