Bradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia risk

Bradycardia prolongs action potential (AP) durations (APD adaptation), enhances dispersion of repolarization (DOR), and promotes tachyarrhythmias. Yet, the mechanisms responsible for enhanced DOR and tachyarrhythmias remain largely unexplored. Ca(2+) transients and APs were measured optically from L...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Jong J., Němec, Jan, Papp, Rita, Strongin, Robert, Abramson, Jonathan J., Salama, Guy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2013
Pynciau:
Cardiac Excitation and Contraction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602772/
https://ncbi.nlm.nih.gov/pubmed/23316064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00787.2012
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