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Mathematical modeling mechanisms of arrhythmias in transgenic mouse heart overexpressing TNF-α
Transgenic mice overexpressing tumor necrosis factor-α (TNF-α mice) possess many of the features of human heart failure, such as dilated cardiomyopathy, impaired Ca(2+) handling, arrhythmias, and decreased survival. Although TNF-α mice have been studied extensively with a number of experimental meth...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360583/ https://ncbi.nlm.nih.gov/pubmed/22081697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00493.2011 |
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