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Bradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia risk

Bradycardia prolongs action potential (AP) durations (APD adaptation), enhances dispersion of repolarization (DOR), and promotes tachyarrhythmias. Yet, the mechanisms responsible for enhanced DOR and tachyarrhythmias remain largely unexplored. Ca(2+) transients and APs were measured optically from L...

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Detalhes bibliográficos
Main Authors: Kim, Jong J., Němec, Jan, Papp, Rita, Strongin, Robert, Abramson, Jonathan J., Salama, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602772/
https://ncbi.nlm.nih.gov/pubmed/23316064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00787.2012
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