Bradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia risk

Bradycardia prolongs action potential (AP) durations (APD adaptation), enhances dispersion of repolarization (DOR), and promotes tachyarrhythmias. Yet, the mechanisms responsible for enhanced DOR and tachyarrhythmias remain largely unexplored. Ca(2+) transients and APs were measured optically from L...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Jong J., Němec, Jan, Papp, Rita, Strongin, Robert, Abramson, Jonathan J., Salama, Guy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2013
Konular:
Cardiac Excitation and Contraction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602772/
https://ncbi.nlm.nih.gov/pubmed/23316064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00787.2012
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