IL-17 induces type V collagen overexpression and EMT via TGF-β-dependent pathways in obliterative bronchiolitis

Obliterative bronchiolitis (OB), a fibrotic airway lesion, is the leading cause of death after lung transplantation. Type V collagen [col(V)] overexpression and IL-17-mediated anti-col(V) immunity are key contributors to OB pathogenesis. Here, we report a previously undefined role of IL-17 in induci...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vittal, Ragini, Fan, Lin, Greenspan, Daniel S., Mickler, Elizabeth A., Gopalakrishnan, Bagavathi, Gu, Hongmei, Benson, Heather L., Zhang, Chen, Burlingham, William, Cummings, Oscar W., Wilkes, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602743/
https://ncbi.nlm.nih.gov/pubmed/23262228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00080.2012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados