IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants

Bronchiolitis obliterans syndrome (BOS), a process of fibro-obliterative occlusion of the small airways in the transplanted lung, is the most common cause of lung transplant failure. We tested the role of cell-mediated immunity to collagen type V [col(V)] in this process. PBMC responses to col(II) a...

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Hoofdauteurs: Burlingham, William J., Love, Robert B., Jankowska-Gan, Ewa, Haynes, Lynn D., Xu, Qingyong, Bobadilla, Joseph L., Meyer, Keith C., Hayney, Mary S., Braun, Ruedi K., Greenspan, Daniel S., Gopalakrishnan, Bagavathi, Cai, Junchao, Brand, David D., Yoshida, Shigetoshi, Cummings, Oscar W., Wilkes, David S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2007
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040314/
https://ncbi.nlm.nih.gov/pubmed/17965778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28031
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