IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants

Bronchiolitis obliterans syndrome (BOS), a process of fibro-obliterative occlusion of the small airways in the transplanted lung, is the most common cause of lung transplant failure. We tested the role of cell-mediated immunity to collagen type V [col(V)] in this process. PBMC responses to col(II) a...

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Autors principals: Burlingham, William J., Love, Robert B., Jankowska-Gan, Ewa, Haynes, Lynn D., Xu, Qingyong, Bobadilla, Joseph L., Meyer, Keith C., Hayney, Mary S., Braun, Ruedi K., Greenspan, Daniel S., Gopalakrishnan, Bagavathi, Cai, Junchao, Brand, David D., Yoshida, Shigetoshi, Cummings, Oscar W., Wilkes, David S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040314/
https://ncbi.nlm.nih.gov/pubmed/17965778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28031
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