CD4 T cells but not Th17 cells are Required for Mouse Lung Transplant Obliterative Bronchiolitis

Lung transplant survival is limited by obliterative bronchiolitis (OB), but the mechanisms of OB development are unknown. Previous studies in a mouse model of orthotopic lung transplantation suggested a requirement for IL-17. We have used this orthotopic mouse model to investigate the source of IL-1...

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Bibliografiske detaljer
Udgivet i:Am J Transplant
Main Authors: Wu, Qiang, Gupta, Pawan Kumar, Suzuki, Hidemi, Wagner, Sarah R., Zhang, Chen, W.Cummings, Oscar, Fan, Lin, Kaplan, Mark H., Wilkes, David S., Shilling, Rebecca A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679154/
https://ncbi.nlm.nih.gov/pubmed/25773063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13215
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