CD4 T cells but not Th17 cells are Required for Mouse Lung Transplant Obliterative Bronchiolitis

Lung transplant survival is limited by obliterative bronchiolitis (OB), but the mechanisms of OB development are unknown. Previous studies in a mouse model of orthotopic lung transplantation suggested a requirement for IL-17. We have used this orthotopic mouse model to investigate the source of IL-1...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Wu, Qiang, Gupta, Pawan Kumar, Suzuki, Hidemi, Wagner, Sarah R., Zhang, Chen, W.Cummings, Oscar, Fan, Lin, Kaplan, Mark H., Wilkes, David S., Shilling, Rebecca A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679154/
https://ncbi.nlm.nih.gov/pubmed/25773063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13215
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