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IL-17A Blockade Attenuates Obliterative Bronchiolitis and IFN-γ Cellular Immune Response in Lung Allografts

Obliterative bronchiolitis (OB), characterized by fibrous obliteration of the small airways, is a major impediment to long-term survival in lung allograft recipients. We found previously that IL-17A is produced primarily by CD4(+) T cells and γδ T cells after lung transplant in a mouse model of orth...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Gupta, Pawan Kumar, Wagner, Sarah R., Wu, Qiang, Shilling, Rebecca A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516289/
https://ncbi.nlm.nih.gov/pubmed/28118023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0154OC
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