Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-β and Associated Transcripts in Pulmonary Fibrosis

RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by progressive scarring and matrix deposition. Recent reports highlight an autoimmune component in IPF pathogenesis. We have reported anti-col(V) immunity in IPF patients. The objective of our study was...

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Bibliografiske detaljer
Main Authors: Vittal, Ragini, Mickler, Elizabeth A., Fisher, Amanda J., Zhang, Chen, Rothhaar, Katia, Gu, Hongmei, Brown, Krista M., Emtiazdjoo, Amir, Lott, Jeremy M., Frye, Sarah B., Smith, Gerald N., Sandusky, George E., Cummings, Oscar W., Wilkes, David S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804565/
https://ncbi.nlm.nih.gov/pubmed/24204629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076451
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