Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-β and Associated Transcripts in Pulmonary Fibrosis

RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by progressive scarring and matrix deposition. Recent reports highlight an autoimmune component in IPF pathogenesis. We have reported anti-col(V) immunity in IPF patients. The objective of our study was...

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Detalhes bibliográficos
Main Authors: Vittal, Ragini, Mickler, Elizabeth A., Fisher, Amanda J., Zhang, Chen, Rothhaar, Katia, Gu, Hongmei, Brown, Krista M., Emtiazdjoo, Amir, Lott, Jeremy M., Frye, Sarah B., Smith, Gerald N., Sandusky, George E., Cummings, Oscar W., Wilkes, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804565/
https://ncbi.nlm.nih.gov/pubmed/24204629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076451
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