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pH-dependent dynamics of complex RNA macromolecules
The role of pH-dependent protonation equilibrium in modulating RNA dynamics and function is one of the key unanswered questions in RNA biology. Molecular dynamics (MD) simulations can provide insight into the mechanistic roles of protonated nucleotides, but it is only capable of modeling fixed proto...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601751/ https://ncbi.nlm.nih.gov/pubmed/23525495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct300942z |
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