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Uncovering pH-Dependent Transient States of Proteins with Buried Ionizable Residues
[Image: see text] The role of pH in regulating biological activity is ubiquitous, and understanding pH-mediated activity has traditionally relied on analyzing static biomolecular structures of highly populated ground states solved near physiological pH. However, recent advances have shown the increa...
Shranjeno v:
| izdano v: | J Am Chem Soc |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2014
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227812/ https://ncbi.nlm.nih.gov/pubmed/24842060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5012564 |
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