Загрузка...
Constant pH Molecular Dynamics Simulations of Nucleic Acids in Explicit Solvent
The nucleosides of adenine and cytosine have pKa values of 3.50 and 4.08, respectively, and are assumed to be unprotonated under physiological conditions. However, evidence from recent NMR and X-Ray crystallography studies has revealed the prevalence of protonated adenine and cytosine in RNA macromo...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277849/ https://ncbi.nlm.nih.gov/pubmed/22337595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct2006314 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|