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pH-Dependent Transient Conformational States Control Optical Properties in Cyan Fluorescent Protein

A recently engineered mutant of cyan fluorescent protein (WasCFP) that exhibits pH-dependent absorption suggests that its tryptophan-based chromophore switches between neutral (protonated) and charged (deprotonated) states depending on external pH. At pH 8.1 the latter gives rise to green fluorescen...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Laricheva, Elena N., Goh, Garrett B., Dickson, Alex, Brooks, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394632/
https://ncbi.nlm.nih.gov/pubmed/25647152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja509233r
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