Splicing mutants and their second-site suppressors at the dihydrofolate reductase locus in Chinese hamster ovary cells.

Point mutants induced with a variety of mutagens at the dihydrofolate reductase (dhfr) locus in Chinese hamster ovary (CHO) cells were screened for aberrantly spliced dhfr mRNA by RNase protection and/or reverse transcriptase coupled with cDNA amplification by the polymerase chain reaction (PCR). Of...

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Publicado en:	Mol Cell Biol
Autores principales:	Carothers, A M, Urlaub, G, Grunberger, D, Chasin, L A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8336736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.5085-5098.1993
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