CUL4B promotes replication licensing by up-regulating the CDK2–CDC6 cascade

Cullin-RING ubiquitin ligases (CRLs) participate in the regulation of diverse cellular processes including cell cycle progression. Mutations in the X-linked CUL4B, a member of the cullin family, cause mental retardation and other developmental abnormalities in humans. Cells that are deficient in CUL...

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Detalhes bibliográficos
Main Authors: Zou, Yongxin, Mi, Jun, Wang, Wenxing, Lu, Juanjuan, Zhao, Wei, Liu, Zhaojian, Hu, Huili, Yang, Yang, Gao, Xiaoxing, Jiang, Baichun, Shao, Changshun, Gong, Yaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601365/
https://ncbi.nlm.nih.gov/pubmed/23479742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201206065
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