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CUL4B promotes replication licensing by up-regulating the CDK2–CDC6 cascade
Cullin-RING ubiquitin ligases (CRLs) participate in the regulation of diverse cellular processes including cell cycle progression. Mutations in the X-linked CUL4B, a member of the cullin family, cause mental retardation and other developmental abnormalities in humans. Cells that are deficient in CUL...
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Asıl Yazarlar: | , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2013
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601365/ https://ncbi.nlm.nih.gov/pubmed/23479742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201206065 |
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