Lack of Cul4b, an E3 Ubiquitin Ligase Component, Leads to Embryonic Lethality and Abnormal Placental Development

Cullin-RING ligases (CRLs) complexes participate in the regulation of diverse cellular processes, including cell cycle progression, transcription, signal transduction and development. Serving as the scaffold protein, cullins are crucial for the assembly of ligase complexes, which recognize and targe...

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Bibliographische Detailangaben
Hauptverfasser: Jiang, Baichun, Zhao, Wei, Yuan, Jupeng, Qian, Yanyan, Sun, Wenjie, Zou, Yongxin, Guo, Chenhong, Chen, Bingxi, Shao, Changshun, Gong, Yaoqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351389/
https://ncbi.nlm.nih.gov/pubmed/22606329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037070
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