Lack of Cul4b, an E3 Ubiquitin Ligase Component, Leads to Embryonic Lethality and Abnormal Placental Development

Cullin-RING ligases (CRLs) complexes participate in the regulation of diverse cellular processes, including cell cycle progression, transcription, signal transduction and development. Serving as the scaffold protein, cullins are crucial for the assembly of ligase complexes, which recognize and targe...

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Autors principals: Jiang, Baichun, Zhao, Wei, Yuan, Jupeng, Qian, Yanyan, Sun, Wenjie, Zou, Yongxin, Guo, Chenhong, Chen, Bingxi, Shao, Changshun, Gong, Yaoqin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351389/
https://ncbi.nlm.nih.gov/pubmed/22606329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037070
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