CUL4B contributes to cancer stemness by repressing tumor suppressor miR34a in colorectal cancer

Given that colorectal cancer stem cells (CCSCs) play key roles in the tumor dormancy, metastasis, and relapse, targeting CCSCs is a promising strategy in cancer therapy. Here, we aimed to identify the new regulators of CCSCs and found that Cullin 4B (CUL4B), which possesses oncogenic properties in m...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Li, Yanjun, Hu, Huili, Wang, Yuxing, Fan, Yujia, Yang, Yang, Guo, Beibei, Xie, Xueyong, Lian, Jiabei, Jiang, Baichun, Han, Bo, Wang, Yanlei, Shao, Changshun, Gong, Yaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018700/
https://ncbi.nlm.nih.gov/pubmed/32054830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0206-3
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