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CUL4B negatively regulates Toll-like receptor-triggered proinflammatory responses by repressing Pten transcription

Toll-like receptors (TLRs) play critical roles in innate immunity and inflammation. The molecular mechanisms by which TLR signaling is fine-tuned remain to be completely elucidated. Cullin 4B (CUL4B), which assembles the CUL4B-RING E3 ligase complex (CRL4B), has been shown to regulate diverse develo...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Song, Yu, Li, Peishan, Qin, Liping, Xu, Zhiliang, Jiang, Baichun, Ma, Chunhong, Shao, Changshun, Gong, Yaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026642/
https://ncbi.nlm.nih.gov/pubmed/31729464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0323-0
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