Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling

Receptor activator of NF-κB (RANK) plays a critical role in osteoclastogenesis, an essential process for the initiation of bone remodeling to maintain healthy bone mass and structure. Although the signaling and function of RANK have been investigated extensively, much less is known about the negativ...

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Bibliographic Details
Main Authors: Xia, Wen-Fang, Tang, Fu-Lei, Xiong, Lei, Xiong, Shan, Jung, Ji-Ung, Lee, Dae-Hoon, Li, Xing-Sheng, Feng, Xu, Mei, Lin, Xiong, Wen-Cheng
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601351/
https://ncbi.nlm.nih.gov/pubmed/23509071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207154
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