Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling

Receptor activator of NF-κB (RANK) plays a critical role in osteoclastogenesis, an essential process for the initiation of bone remodeling to maintain healthy bone mass and structure. Although the signaling and function of RANK have been investigated extensively, much less is known about the negativ...

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Detalhes bibliográficos
Main Authors: Xia, Wen-Fang, Tang, Fu-Lei, Xiong, Lei, Xiong, Shan, Jung, Ji-Ung, Lee, Dae-Hoon, Li, Xing-Sheng, Feng, Xu, Mei, Lin, Xiong, Wen-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601351/
https://ncbi.nlm.nih.gov/pubmed/23509071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207154
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