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VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation
BACKGROUND: Vacuolar protein sorting 35 (VPS35), a key component of retromer, plays an important role in endosome-to-Golgi retrieval of membrane proteins. Dysfunction of VPS35/retromer is a risk factor for neurodegenerative disorders, including AD (Alzheimer’s disease) and PD (Parkinson’s disease)....
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| Publicado no: | Mol Brain |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628247/ https://ncbi.nlm.nih.gov/pubmed/26521016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0156-4 |
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