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Microglial VPS35 deficiency regulates microglial polarization and decreases ischemic stroke-induced damage in the cortex
BACKGROUND: Vacuolar sorting protein 35 (VPS35), a critical component of retromer, is essential for selective endosome-to-Golgi retrieval of membrane proteins. It is highly expressed in microglial cells, in addition to neurons. We have previously demonstrated microglial VPS35’s functions in preventi...
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| Pubblicato in: | J Neuroinflammation |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6880612/ https://ncbi.nlm.nih.gov/pubmed/31771656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1633-y |
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