p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis

The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated. This may result from alterations in TP53 family members, including the TP53 homologue TP63. Here we demonstrate that TP...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Matin, Rubeta N., Chikh, Anissa, Law Pak Chong, Stephanie, Mesher, David, Graf, Manuela, Sanza’, Paolo, Senatore, Valentina, Scatolini, Maria, Moretti, Francesca, Leigh, Irene M., Proby, Charlotte M., Costanzo, Antonio, Chiorino, Giovanna, Cerio, Rino, Harwood, Catherine A., Bergamaschi, Daniele
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600906/
https://ncbi.nlm.nih.gov/pubmed/23420876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121439
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars