p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response

Hyperproliferative keratinocytes induced by trauma, hyperkeratosis and/or inflammation display molecular signatures similar to those of palmoplantar epidermis. Inherited gain-of-function mutations in RHBDF2 (encoding iRHOM2) are associated with a hyperproliferative palmoplantar keratoderma and squam...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Arcidiacono, Paola, Webb, Catherine M., Brooke, Matthew A., Zhou, Huiqing, Delaney, Paul J., Ng, Keat-Eng, Blaydon, Diana C., Tinker, Andrew, Kelsell, David P., Chikh, Anissa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844915/
https://ncbi.nlm.nih.gov/pubmed/29523849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03470-y
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