טוען...

Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy

IL-4 plays critical roles in allergic disorders, including food hypersensitivity. The direct effects of the cytokine on the survival and function of mast cells, the key effectors of food anaphylaxis, have not been established. In this study we demonstrate that IL-4 induces a marked intestinal mastoc...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Burton, Oliver T, Darling, Alanna R, Zhou, Joseph S, Noval-Rivas, Magali, Jones, Tatiana G, Gurish, Michael F, Chatila, Talal A, Oettgen, Hans C
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600405/
https://ncbi.nlm.nih.gov/pubmed/23149659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.112
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