Inhibition of Immunoglobulin E signals during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells

Immunoglobulin E (IgE) antibodies are known for triggering immediate hypersensitivity reactions such as food anaphylaxis. In this study, we tested whether they might additionally function to amplify nascent antibody and T helper 2 (Th2) cell-mediated responses to ingested proteins and if blocking Ig...

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Huvudupphovsmän: Burton, Oliver T., Noval-Rivas, Magali, Zhou, Joseph S., Logsdon, Stephanie L., Darling, Alanna R., Koleoglou, Kyle J., Roers, Axel, Houshyar, Hani, Crackower, Michael A., Chatila, Talal A., Oettgen, Hans C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123130/
https://ncbi.nlm.nih.gov/pubmed/25017467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.05.017
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