Oral immunotherapy induces IgG antibodies that act via FcγRIIb to suppress IgE-mediated hypersensitivity

BACKGROUND: Food anaphylaxis is triggered by specific IgE antibodies. Paradoxically, some individuals with significant IgE levels can ingest allergenic foods without incident. Similarly, subjects completing oral immunotherapy (OIT) tolerate food challenges despite persistent high-titer food-specific...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Burton, Oliver T., Logsdon, Stephanie L., Zhou, Joseph S., Medina-Tamayo, Jaciel, Abdel-Gadir, Azza, Rivas, Magali Noval, Koleoglou, Kyle J., Chatila, Talal A., Schneider, Lynda C., Rachid, Rima, Umetsu, Dale T., Oettgen, Hans C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261076/
https://ncbi.nlm.nih.gov/pubmed/25042981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.05.042
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