The synthetic triterpenoid, RTA405, increases glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells

Bardoxolone methyl, a synthetic triterpenoid, improves the estimated glomerular filtration rate (GFR) in patients with chornic kidney disease and type 2 diabetes. Since the contractile activity of mesangial cells may influence glomerular filtration, we evaluated the effect of the synthetic triterpen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ding, Yanfeng, Stidham, Rhesa, Bumeister, Ron, Trevino, Isaac, Winters, Ali, Sprouse, Marc, Ding, Min, Ferguson, Deborah A., Meyer, Colin J., Wigley, W. Christian, Ma, Rong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600401/
https://ncbi.nlm.nih.gov/pubmed/23235569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.393
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