Short-Term Treatment With Rapamycin and Dietary Restriction Have Overlapping and Distinctive Effects in Young Mice

Because rapamycin, an inhibitor of the nutrient sensor mammalian target of rapamycin, and dietary restriction both increase life span of mice, it has been hypothesized that they act through similar mechanisms. To test this hypothesis, we compared various biological parameters in dietary restriction...

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Bibliografiske detaljer
Main Authors: Fok, Wilson C., Zhang, Yiqiang, Salmon, Adam B., Bhattacharya, Arunabh, Gunda, Rakesh, Jones, Dean, Ward, Walter, Fisher, Kathleen, Richardson, Arlan, Pérez, Viviana I.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598360/
https://ncbi.nlm.nih.gov/pubmed/22570137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gls127
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